Leptin, Adiponectin & Ghrelin: Why You Should Care

By High Intensity Health

Summary

The speaker discusses leptin and adiponectin's role in weight loss, immune function, and inflammation. They emphasize strategies to regulate leptin for better health outcomes.

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One-Sentence Takeaway

Leptin plays a critical role in both metabolism and inflammation, making it essential to address for sustainable weight loss and health.

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"Leptin is very intimately involved with inflammation, not only just obesity."
"The more overweight you become, the more inflamed you become."
"Skinny fat people may look lean, but on the inside, they’re literally dying."
"Leptin is released from your fat cells; the more fat cells you have, the more leptin you release."
"Leptin resistance occurs when the brain’s receptors downregulate due to excess leptin."
"Leptin is involved in regulating T regulatory cells, which manage inflammation."
"Excessive leptin suppresses T regulatory cells, leading to increased inflammation."
"People say ‘calories in, calories out,’ but if you're inflamed, you won’t burn fat."
"Pro-inflammatory immune cells thrive on sugar and make you insulin resistant."
"Leptin is linked with C-reactive protein and inflammation, making fat loss harder."
"Adiponectin is anti-inflammatory and promotes insulin sensitivity."
"Omega-3 fats like fish oil and krill oil help increase adiponectin levels."
"Circadian rhythms, such as consistent sleep and sunlight exposure, regulate leptin."
"Resistance training helps with leptin sensitivity and metabolic signaling pathways."
"Obesity or chronic inflammation impairs insulin sensitivity, contributing to metabolic dysfunction."
"Leptin’s role in immune regulation is critical for managing autoimmunity and chronic diseases."

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